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| Management number | 204569943 | Release Date | 2025/10/14 | List Price | $224.25 | Model Number | 204569943 | ||
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Apoquel (oclacitinib) is a medication used to manage pruritus associated with allergic dermatitis and atopic dermatitis in dogs. This medication offers rapid relief within hours and is suitable for long-term use, ensuring your pet enjoys a comfortable, itch-free life. Trusted by veterinarians, Apoquel is renowned for its efficacy and safety in treating various types of dermatitis in dogs.
Apoquel is available in both oral and chewable tablet forms. Unlike other allergy medications, it targets the source of irritation, relieving itch and inflammation by addressing the underlying causes. It begins to alleviate symptoms within 4 hours and controls itching effectively within 24 hours.
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Prescription items are NON-RETURNABLE and NON-REFUNDABLE.
The active component of Apoquel is oclacitinib, which is classified as a Janus kinase (JAK1) inhibitor. The mechanism of action of Apoquel is to inhibit the actions of Janus kinase, a crucial signal that causes inflammation and itching in dogs with allergies.
This lessens the cellular source of itching and minimizes the impact of some inflammatory signals in the body. Consequently, dogs with allergies who receive Apoquel experience reduced itching and scratching. Allergy-induced skin irritation is also reduced.
Apoquel delivers numerous benefits to both pets and their owners:
Proper dosing and administration are key to the effectiveness of Apoquel:
Initial Dosage: Administer 0.4-0.6 mg/kg twice daily for up to 14 days. This initial period helps bring symptoms under control quickly.
Maintenance Dosage: After the initial period, reduce to once daily for ongoing management. This maintenance dose helps keep allergic symptoms at bay over the long term.

The most common side effects include:
Both of these are typically short-term and resolve on their own. However, there are some less common side effects, such as:
Apoquel is not recommended for dogs under 12 months of age or those with serious infections. It should also not be used in breeding, pregnant, or nursing dogs.
Dogs receiving APOQUEL CHEWABLE should be monitored for the development of infections, including demodicosis, and neoplasia.
The APOQUEL CHEWABLE has not been evaluated in combination with glucocorticoids, cyclosporine, or other systemic immunosuppressive agents.
This product is not for human use.
Keep this and all drugs out of reach of children.
For use in dogs only.
Wash hands immediately after handling the tablets.
APOQUEL CHEWABLE modulates the immune system.
APOQUEL CHEWABLE is not for use in dogs with serious infections.
APOQUEL CHEWABLE may increase susceptibility to infection, including demodicosis, and exacerbation of neoplastic conditions.
New neoplastic conditions (benign and malignant) were observed in dogs treated with oclacitinib film-coated tablets (FCT) during clinical studies and have been reported in the post-approval period.
Consider the risks and benefits of treatment before initiating APOQUEL CHEWABLE in dogs with a history of recurrent serious infections or recurrent demodicosis or neoplasia.
Keep APOQUEL CHEWABLE in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.
APOQUEL CHEWABLE should be stored at controlled room temperature between 20° to 25°C (68° to 77°F) with excursions between 15° to 40°C (59° to 104°F).
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The only Janus kinase (JAK) inhibitor currently licensed for use in dogs is Apoquel. It is used to treat atopic dermatitis and relieve itch brought on by allergic dermatitis.
The most often given oral medication for allergic itch1, Apoquel, works well for
Apoquel Chewable is used to treat atopic dermatitis and allergic dermatitis, among other conditions that cause irritation and itching. However, it cannot be used in breeding, pregnant, or nursing dogs.
If your pet has ever experienced an allergic response to a drug, let your veterinarian know.
Apoquel Chewable may make your furry friend more vulnerable to infections, such as demodicosis.
Additionally, it might make neoplastic diseases worse. Several adverse effects that were recorded included lethargy, vomiting, diarrhea, anorexia, and new cutaneous or subcutaneous tumors. With maintained dosage, the majority of cases of diarrhea, vomiting, anorexia, and lethargy resolved on their own.
Give the missed dose with food as soon as you remember and resume a regular dosing schedule.
Contact your veterinarian immediately.
Dogs with severe illnesses or those under 12 months old shouldn't be given Apoquel Chewable.
It is not recommended to use Apoquel Chewable on dogs who are pregnant or nursing canines.
Apoquel Chewable has not been tested in conjunction with cyclosporine, glucocorticoids, or any other systemic immunosuppressive medication.
It is important to keep an eye out for infections in dogs on Apoquel Chewable, such as demodicosis and neoplasia.
It depends from dog to dog according to their age, weight, and medical history. Talk to your veterinarian before giving any prescription or over-the-counter medications.
As of now, there is no generic equivalent for oclacitinib (Apoquel) for dogs. Apoquel is the brand name and is manufactured by Zoetis.
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